What is difference between a homokaryon and a heterokaryon

1. If normal cells were isolated many years ago and have been maintained in the lab through subculturing, would you expect this cell line now to be normal or transformed? why?

2. What is the difference between a homokaryon and a heterokaryon?

3. What role does PEG (polyethylene glycol) play in the formation of homokaryons and heterokaryons?

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